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Appendix 1 - Carcinogenic Materials |
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Alkylating agents: -halo ethers |
Natural products (including antitumor drugs) |
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*bis(chloromethyl)ether |
adiramycin |
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*methyl chloromethyl ether |
aflatoxins |
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Alkylating agents: sulfonates |
bleomycin |
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*1,4-butanediol dimethanesulfonate |
cisplatin |
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diethyl sulfate |
progesterone |
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dimethyl sulfate |
reserpine |
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ethyl methanesulfonate |
safrole |
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methyl methanesulfonate |
Miscellaneous organic compounds |
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methyl trifluoromethanesulfonate |
*formaldehyde (gas) |
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1,3-propanesultone |
acetaldehyde |
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Alkylating agents: epoxides |
1,4-dioxane |
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*ethylene oxide |
ethyl carbamate (urethane) |
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diepoxybutane |
hexamethylphosphoramide |
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epichlorohydrin |
2-nitropropane |
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propylene oxide |
styrene |
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styrene oxide |
thiourea |
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Alkylating agents: aziridines |
thioacetamide |
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*ethylenimine |
Miscellaneous inorganic compounds |
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2-methylaziridine |
*arsenic and certain arsenic compounds |
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Alkylating agents: diazo, azo, and azoxy compounds |
*chromium and certain chromium compounds |
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4-dimethylaminoazobenzene |
*thorium dioxide |
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Alkyl |
beryllium and certain beryllium compounds |
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*acrylonitrile acrolein |
cadmium and certain cadmium compounds |
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ethyl acrylate |
lead and certain lead compounds |
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Acrylating agents |
nickel and certain nickel compounds selenium sulfide |
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*-propiolactone |
Partial List of Select Carcinogens |
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-butyrolactone |
2-acetylaminofluorene |
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dimethylcarbamoyl chloride |
acrylonitrile |
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Organohalogen compounds |
4-aminobiphenyl |
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*1,2-dibromo-3-chloropropane |
analgesic mixtures containing phenacetin |
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*mustard gas (bis(2-chloroethyl)sulfide) |
arsenic and certain arsenic compounds |
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*vinyl chloride |
asbestos |
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carbon tetrachloride |
azathioprine |
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chloroform |
benzene |
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3-chloro-2-methylpropene |
benzidine |
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1,2-dibromoethane |
betel quid containing tobacco |
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1,4-dichlorobenzene |
1,4-butanediol dimethylsulfonate (myleran) |
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1,2-dichloroethane |
chlorambucil |
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2,2-dichloroethane |
chloromethyl methyl ether |
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1,3-dichloropropene |
chromium (VI) and certain chromium compounds |
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hexachlorobenzene |
coal-tar pitches |
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methyl iodide |
coal tars |
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tetrachloroethylene |
conjugated estrogens |
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trichloroethylene |
cyclophosphamide |
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2,4,6-trichlorophenol |
1,2-dibromo-3-chloropropane |
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Hydrazines |
3,3'-dichlorobenzidine (and its salts) |
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hydrazine (and hydrazine salts) 1,2-diethylhydrazine |
diethylstilbestrol |
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1,1-dimethylhydrazine |
dimethylaminoazobenzene |
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1,2-dimethylhydrazine |
ethylene oxide |
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N-nitroso compounds |
ethylenimine |
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N-nitroso-N-alkylureas |
melphalan |
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*N-nitrosodimethylamine |
formaldehyde |
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Aromatic amines |
methoxsalen with ultraviolet A therapy |
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*4-aminobiphenyl |
4,4'-methylene-bis(2- chloroaniline) |
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*benzidine (p,p'-diaminobiphenyl) |
mustard gas |
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*-naphthylamine |
N,N'-cis(chloroethyl)-2- naphthylamine (chloronaphazine) |
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*-naphthylamine |
-naphthylamine |
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aniline |
-naphthylamine |
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o-anisidine (2-methoxyaniline) |
4-nitrobiphenyl |
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2,4-diaminotoluene |
N-nitrosodimethylamine |
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o-toluidine |
-propiolactone |
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Aromatic hydrocarbons |
shale oils |
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*benzene |
smokeless tobacco products (oral use) |
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benz(a)anthracene |
soots and soot extracts |
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benzo(a)pyrene |
thorium dioxide |
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tobacco smoke |
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treosulphan |
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vinyl chloride |
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