Chemical Appendix 1

Appendix 1 - Carcinogenic Materials

Alkylating agents: -halo ethers

Natural products (including antitumor drugs)

*bis(chloromethyl)ether

adiramycin

*methyl chloromethyl ether

aflatoxins

Alkylating agents: sulfonates

bleomycin

*1,4-butanediol dimethanesulfonate

cisplatin

diethyl sulfate

progesterone

dimethyl sulfate

reserpine

ethyl methanesulfonate

safrole

methyl methanesulfonate

Miscellaneous organic compounds

methyl trifluoromethanesulfonate

*formaldehyde (gas)

1,3-propanesultone

acetaldehyde

Alkylating agents: epoxides

1,4-dioxane

*ethylene oxide

ethyl carbamate (urethane)

diepoxybutane

hexamethylphosphoramide

epichlorohydrin

2-nitropropane

propylene oxide

styrene

styrene oxide

thiourea

Alkylating agents: aziridines

thioacetamide

*ethylenimine

Miscellaneous inorganic compounds

2-methylaziridine

*arsenic and certain arsenic compounds

Alkylating agents: diazo, azo, and azoxy compounds

*chromium and certain chromium compounds

4-dimethylaminoazobenzene

*thorium dioxide

Alkyl

beryllium and certain beryllium compounds

*acrylonitrile acrolein

cadmium and certain cadmium compounds

ethyl acrylate

lead and certain lead compounds

Acrylating agents

nickel and certain nickel compounds selenium sulfide

*-propiolactone

Partial List of Select Carcinogens

-butyrolactone

2-acetylaminofluorene

dimethylcarbamoyl chloride

acrylonitrile

Organohalogen compounds

4-aminobiphenyl

*1,2-dibromo-3-chloropropane

analgesic mixtures containing phenacetin

*mustard gas (bis(2-chloroethyl)sulfide)

arsenic and certain arsenic compounds

*vinyl chloride

asbestos

carbon tetrachloride

azathioprine

chloroform

benzene

3-chloro-2-methylpropene

benzidine

1,2-dibromoethane

betel quid containing tobacco

1,4-dichlorobenzene

1,4-butanediol dimethylsulfonate (myleran)

1,2-dichloroethane

chlorambucil

2,2-dichloroethane

chloromethyl methyl ether

1,3-dichloropropene

chromium (VI) and certain chromium compounds

hexachlorobenzene

coal-tar pitches

methyl iodide

coal tars

tetrachloroethylene

conjugated estrogens

trichloroethylene

cyclophosphamide

2,4,6-trichlorophenol

1,2-dibromo-3-chloropropane

Hydrazines

3,3'-dichlorobenzidine (and its salts)

hydrazine (and hydrazine salts) 1,2-diethylhydrazine

diethylstilbestrol

1,1-dimethylhydrazine

dimethylaminoazobenzene

1,2-dimethylhydrazine

ethylene oxide

N-nitroso compounds

ethylenimine

N-nitroso-N-alkylureas

melphalan

*N-nitrosodimethylamine

formaldehyde

Aromatic amines

methoxsalen with ultraviolet A therapy

*4-aminobiphenyl

4,4'-methylene-bis(2- chloroaniline)

*benzidine (p,p'-diaminobiphenyl)

mustard gas

*-naphthylamine

N,N'-cis(chloroethyl)-2- naphthylamine (chloronaphazine)

*-naphthylamine

-naphthylamine

aniline

-naphthylamine

o-anisidine (2-methoxyaniline)

4-nitrobiphenyl

2,4-diaminotoluene

N-nitrosodimethylamine

o-toluidine

-propiolactone

Aromatic hydrocarbons

shale oils

*benzene

smokeless tobacco products (oral use)

benz(a)anthracene

soots and soot extracts

benzo(a)pyrene

thorium dioxide

 

tobacco smoke

treosulphan

vinyl chloride

 

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