If you are going to be away from your computer or your office, you can ask Outlook to automatically reply to a sender. In this way, you can let people know, for example, that you are away on vacation for the week.

First you have to make sure that your Inbox is the active folder. Click on View, Folder List if it's not already visible. Now click the Inbox folder to select it.

Choose Tools, Out of Office Assistant.

Click I am currently Out of the Office. Enter the message that you would like the assistant to automatically send for you.

Click OK.